Issues

• Impossible to disable bindgen of hts-sys

  rust-bio/rust-htslib#512 · Filter by author berndbohmeier opened on Jun 15, 2026

• SIG SEGV when using custom allocator, mimalloc

  rust-bio/rust-htslib#510 · Filter by author Crispy13 opened on Mar 24, 2026

• Bioconductor build fails due to htslib version problems

  rust-bio/rust-htslib#508 · Filter by author stela2502 opened on Mar 6, 2026
  5

• visibility changed in recent commit

  rust-bio/rust-htslib#502 · Filter by author brentp opened on Dec 20, 2025
  5

• panic in index_stats for tid = -1

  rust-bio/rust-htslib#490 · Filter by author wdecoster opened on Oct 5, 2025

• hfile_set_blksize not exposed

  rust-bio/rust-htslib#489 · Filter by author JulianDicken opened on Sep 19, 2025

• Failed to fetch region: fetch converts u64 to i64.

  rust-bio/rust-htslib#487 · Filter by author SebastianDall opened on Sep 9, 2025

• BAQ re-alignment

  rust-bio/rust-htslib#482 · Filter by author berndbohmeier opened on Aug 11, 2025
  2

• Add support for bam_aux_update_str(), bam_aux_update_int(), bam_aux_update_float(), bam_aux_update_array()

  rust-bio/rust-htslib#480 · Filter by author ghuls opened on Aug 5, 2025
  1

• Using records iterator instead of read interface results in invalid memory access when reading a bam file and sending bam records over a thread

  rust-bio/rust-htslib#479 · Filter by author uray-scalebio opened on Jul 22, 2025

• How to add new INFO fileds into VCF

  rust-bio/rust-htslib#475 · Filter by author AuroUTU opened on May 4, 2025

• Add public constructor for public structs

  rust-bio/rust-htslib#472 · Filter by author TedBrookings opened on Apr 10, 2025

• Support for using Cursor?

  rust-bio/rust-htslib#471 · Filter by author Crispy13 opened on Mar 23, 2025

• Performance degradation with VCF Reader Apple Silicon

  rust-bio/rust-htslib#464 · Filter by author mwiewior opened on Jan 27, 2025
  1

• Question about bam::IndexedReader::fetch()

  rust-bio/rust-htslib#463 · Filter by author epiliper opened on Jan 26, 2025

• Question about building rust-htslib with conda-installed dependencies

  rust-bio/rust-htslib#462 · Filter by author wm75 opened on Jan 16, 2025
  1

• Multiple unsound problems in bcf crate

  rust-bio/rust-htslib#459 · Filter by author lwz23 opened on Dec 5, 2024
  7

• Is there any way to tell where in the file the reader is ?

  rust-bio/rust-htslib#456 · Filter by author JulianDicken opened on Nov 27, 2024

• Update libdeflate (mirroring issue in hts-sys)

  rust-bio/rust-htslib#454 · Filter by author davidlougheed opened on Nov 20, 2024
  1

• rust-htslib panics on bam record.contig() call

  rust-bio/rust-htslib#446 · Filter by author xosxos opened on Nov 5, 2024
  1

• [Feature request] query_position_or_next method for Alignment

  rust-bio/rust-htslib#445 · Filter by author Crispy13 opened on Oct 29, 2024

• Cargo test leading to "unsafe precondition(s) violated"

  rust-bio/rust-htslib#442 · Filter by author ebioman opened on Oct 11, 2024

• Embedding the reference into CRAM outputs (embed_ref=1)

  rust-bio/rust-htslib#441 · Filter by author mrvollger opened on Oct 9, 2024

• Weird reference_end() value

  rust-bio/rust-htslib#436 · Filter by author Crispy13 opened on Jul 9, 2024

• 0.47.0 introduced a dependency on libclang

  rust-bio/rust-htslib#434 · Filter by author DaGaMs opened on Jul 5, 2024
  10