The Antibiotic Resistance Ontology describes antibiotic resistance genes and mutations, their products, mechanisms, and associated phenotypes, as well as antibiotics and their molecular targets. It is integrated with the Comprehensive Antibiotic Resistance Database (https://card.mcmaster.ca), a curated resource containing high-quality reference data on the molecular basis of antimicrobial resistance.
Ontologies at the Comprehensive Antibiotic Resistance Database are freely available under the Creative Commons CC-BY license version 4.0.
The ARO is under active curation by the CARD curation team, including new terms, relationships, and corrections. Updates are released every 3-6 months here and at the CARD website. This repo (https://github.com/arpcard/aro) does not accept pull requests, but instead only reflects the latest release at card.mcmaster.ca. Please request additions or modifications to the ARO either here via https://github.com/arpcard/aro/issues or at https://github.com/arpcard/amr_curation. The curation team will work with you to incorporate your suggestions into the next release of the ARO.
The latest version of the ontology can always be found at the OBO Foundry PURL:
http://purl.obolibrary.org/obo/aro.owl
The ontology file (aro.owl) is released in RDF/XML, the canonical OWL serialization required by the OBO Foundry (principle FP-002).
Please contact us at card@mcmaster.ca.