Skip to content

Drop each complex without an ortholog under the drop policy - #199

Open
edkerk wants to merge 1 commit into
developfrom
feat/drop-per-complex
Open

edkerk wants to merge 1 commit into
developfrom
feat/drop-per-complex

Conversation

@edkerk

@edkerk edkerk commented Nov 5, 2026

Copy link
Copy Markdown
Collaborator

get_model_from_homology with complex_policy="drop" removes each complex that has a subunit without an ortholog, and removes the reaction only when no complex remains. For the rule (A and B) or (C and D) without an ortholog of B, the draft has the orthologs of C and D. Before, the reaction was removed as soon as one subunit had no ortholog. A complex that contains another complete complex is kept, and a gene that several complexes share removes only the complexes in which it has no ortholog.

The same policy is implemented in RAVEN#25.

The policy drop removes each complex that has a subunit without an ortholog and removes the reaction when no complex remains. It removed the reaction as soon as one subunit had no ortholog.

This branch has not been deployed

No deployments
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

1 participant